Job Details

Vice President or Senior Vice President, Clinical Development Operations

Watertown, MA

Who we are:

Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Bostons top workplaces for the past several years. For more information about our science, pipeline and people, please visitwww.kymeratx.com or follow us onX (formerly Twitter) orLinkedIn .

How we work:

• PIONEER: We are courageous, resilient and rigorous in our mission to improve patients lives through our revolutionary degrader medicines.
• COLLABORATE: We value trust + transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
• BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.

How youll contribute:

• Provide visionary leadership across Clinical Development Operations, cultivating a high-performing, collaborative culture.
• Oversee end-to-end global trial execution across multiple programs and phases, with a focus on quality, timeliness, and budget adherence.
• Build and scale operational capabilities, including process optimization, systems implementation, and inspection readiness.
• Collaborate cross-functionally with Clinical Development, PM and Program Leader, Regulatory, Data Sciences, Safety, and CMC to align program strategy with operational delivery.
• Lead vendor strategy and governance for CROs, central labs, and other external partners, ensuring accountability and performance.
• Actively contribute to strategic planning, scenario modeling, and regulatory submissions for global programs.
• Ensure trials meet the highest standards of GCP compliance, patient safety, and data integrity.
• Serve as a key member of Kymeras development leadership team, and on our R&D program review meetings, helping shape the broader clinical strategy and culture.

Skills and experience youll bring:

• Advanced degree in life sciences or related field (PhD, PharmD, or MD preferred).
• 15+ years of clinical operations leadership experience, with a strong track record managing global trials across phases (esp. Ph2Ph3), ideally in immunology/inflammation and/or large scale trials.
• Demonstrated success building and leading large, multi-disciplinary teams in dynamic, matrixed environments.
• Expertise in vendor oversight, budget and resource planning, and cross-functional team alignment.
• Deep understanding of regulatory requirements and global GCP/ICH guidelines.
• Inspirational people leader with excellent communication, decision-making, and change management skills.
• Mission-driven, solutions-oriented, and thrives in a fast-paced biotech setting.

Kymera Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.

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